SNX15 anticorps

N° du produit ABIN7264751

Détail du produit anti-SNX15 anticorps

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNX15 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SNX15 (NP_037438.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SNX15

Antigène: SNX15 (Sorting Nexin 15 (SNX15))

Autre désignation: SNX15 (SNX15 Produits)

Synonymes: anticorps SNX15, anticorps hsaf001435, anticorps snx15, anticorps MGC154249, anticorps HSAF001435, anticorps 1500032B08Rik, anticorps E130013C21Rik, anticorps sorting nexin 15, anticorps sorting nexin 15 S homeolog, anticorps SNX15, anticorps snx15.S, anticorps snx15, anticorps Snx15

Sujet: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. Overexpression of this gene results in a decrease in the processing of insulin and hepatocyte growth factor receptors to their mature subunits. This decrease is caused by the mislocalization of furin, the endoprotease responsible for cleavage of insulin and hepatocyte growth factor receptors. This protein is involved in endosomal trafficking from the plasma membrane to recycling endosomes or the trans-Golgi network. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ADP-ribosylation factor-like 2 (ARL2) gene.

ID gène: 29907

UniProt: Q9NRS6