SEC31A anticorps

N° du produit ABIN7264783

Détail du produit anti-SEC31A anticorps

Antigène: SEC31A (SEC31 Homolog A (SEC31A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEC31A est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SEC31A (NP_055748.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SEC31A

Antigène: SEC31A (SEC31 Homolog A (SEC31A))

Autre désignation: SEC31A (SEC31A Produits)

Synonymes: anticorps ABP125, anticorps ABP130, anticorps HSPC334, anticorps SEC31L1, anticorps Sec31l1, anticorps VAP1, anticorps 1810024J13Rik, anticorps AU042160, anticorps HSPC275, anticorps cb354, anticorps sec31p, anticorps zgc:63547, anticorps SEC31 homolog A, COPII coat complex component, anticorps Sec31 homolog A (S. cerevisiae), anticorps SEC31A, anticorps Sec31a, anticorps sec31a

Sujet: The protein encoded by this gene shares similarity with the yeast Sec31 protein, and is a component of the outer layer of the coat protein complex II (COPII). The encoded protein is involved in vesicle budding from the endoplasmic reticulum (ER) and contains multiple WD repeats near the N-terminus and a proline-rich region in the C-terminal half. It associates with the protein encoded by the SEC13 homolog, nuclear pore and COPII coat complex component (SEC13), and is required for ER-Golgi transport. Monoubiquitylation of this protein by CUL3-KLHL12 was found to regulate the size of COPII coats to accommodate unusually shaped cargo. Alternative splicing results in multiple transcript variants encoding different isoforms.

Poids moléculaire:

Observed_MW: 165 kDa

Calculated_MW: 56 kDa/105-134 kDa

ID gène: 22872

UniProt: O94979

Pathways: ER-Nucleus Signaling