PHLPP1 anticorps

N° du produit ABIN7264821

Détail du produit anti-PHLPP1 anticorps

Antigène: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHLPP1 est non-conjugé

Application: Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human PHLPP1 (NP_919431.2).

Isotype: IgG

Information d'application

Indications d'application: IF 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PHLPP1

Antigène: PHLPP1 (PH Domain and Leucine Rich Repeat Protein Phosphatase 1 (PHLPP1))

Autre désignation: PHLPP1 (PHLPP1 Produits)

Synonymes: anticorps PHLPP, anticorps PLEKHE1, anticorps SCOP, anticorps AI836256, anticorps Phlpp, anticorps Plekhe1, anticorps mKIAA0606, anticorps Scop, anticorps PH domain and leucine rich repeat protein phosphatase 1, anticorps PHLPP1, anticorps phlpp1, anticorps Phlpp1

Sujet: This gene encodes a member of the serine/threonine phosphatase family. The encoded protein promotes apoptosis by dephosphorylating and inactivating the serine/threonine kinase Akt, and functions as a tumor suppressor in multiple types of cancer. Increased expression of this gene may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

ID gène: 23239

UniProt: O60346

Pathways: Signalisation PI3K-Akt, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway