SOCS6 anticorps

N° du produit ABIN7264978

Détail du produit anti-SOCS6 anticorps

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOCS6 est non-conjugé

Application: Immunohistochemistry (IHC)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human SOCS6 (NP_004223.2).

Isotype: IgG

Information d'application

Indications d'application: IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur SOCS6

Antigène: SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))

Autre désignation: SOCS6 (SOCS6 Produits)

Synonymes: anticorps CIS-4, anticorps CIS4, anticorps HSPC060, anticorps SOCS-4, anticorps SOCS-6, anticorps SOCS4, anticorps SSI4, anticorps STAI4, anticorps STATI4, anticorps socs6, anticorps MGC81477, anticorps SOCS6, anticorps 1500012M23Rik, anticorps 5830401B18Rik, anticorps AI447482, anticorps Cis4, anticorps Cish4, anticorps Socs4, anticorps socs6l, anticorps zgc:64107, anticorps wu:fb77f06, anticorps suppressor of cytokine signaling 6, anticorps suppressor of cytokine signaling 6 L homeolog, anticorps suppressor of cytokine signaling, anticorps suppressor of cytokine signaling 6b, anticorps SOCS6, anticorps Socs6, anticorps socs6.L, anticorps socs6, anticorps socs6b

Sujet: The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines.

ID gène: 9306

UniProt: O14544

Pathways: Signalistation JAK/STAT, Carbohydrate Homeostasis