Fibulin 5 anticorps

N° du produit ABIN7264982

Détail du produit anti-Fibulin 5 anticorps

Antigène: Fibulin 5 (FBLN5)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fibulin 5 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Attributs du produit: Polyclonal Antibody

Purification: Affinity purification

Immunogène: Recombinant fusion protein of human FBLN5 (NP_006320.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000 IF 1:50-1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Fibulin 5

Antigène: Fibulin 5 (FBLN5)

Autre désignation: FBLN5 (FBLN5 Produits)

Synonymes: anticorps zgc:103575, anticorps FBLN5, anticorps MGC108414, anticorps Fibulin-5, anticorps DKFZp469K0327, anticorps ADCL2, anticorps ARCL1A, anticorps ARMD3, anticorps DANCE, anticorps EVEC, anticorps FIBL-5, anticorps UP50, anticorps A55, anticorps fibulin 5, anticorps fbln5, anticorps FBLN5, anticorps Fbln5

Sujet: The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Poids moléculaire:

Observed_MW: 72 kDa

Calculated_MW: 50 kDa

ID gène: 10516

UniProt: Q9UBX5

Pathways: SARS-CoV-2 Protein Interactome