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CHEK1 anticorps (pSer280)
CHEK1
Reactivité: Humain, Souris, Rat
IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7265022
Détail du produit anti-CHEK1 anticorps
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Antigène
Voir toutes CHEK1 Anticorps
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Épitope
Tous les épitopes à travers CHEK1 Anticorps.
pSer280
Reactivité
Toutes les réactivités sur CHEK1 Anticorps
Humain, Souris, Rat
Hôte
Toutes les hôtes sur CHEK1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CHEK1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CHEK1 Anticorps
Cet anticorp CHEK1 est non-conjugé
Application
Tous les applications à travers CHEK1 Anticorps.
Immunohistochemistry (IHC), Immunofluorescence (IF)
Attributs du produit
Phosphorylated antibody
Purification
Affinity purification
Immunogène
A synthetic phosphorylated peptide around S280 of human CHEK1 (NP_001265.2).
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
IHC 1:50-1:200 IF 1:50-1:200
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Concentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur CHEK1
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Antigène
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Autre désignation
CHEK1 (CHEK1 Produits )
Synonymes
anticorps An08g10320, anticorps AO090003000441, anticorps CHK1, anticorps chk1, anticorps C85740, anticorps Chk1, anticorps rad27, anticorps id:ibd2720, anticorps zgc:56093, anticorps CHEK1, anticorps checkpoint kinase 1, anticorps serine/threonine-protein kinase chk1, anticorps serine/threonine-protein kinase Chk1, anticorps CAMK/CAMKL/CHK1 protein kinase Chk1, anticorps checkpoint kinase 1 S homeolog, anticorps CHEK1, anticorps ANI_1_2436074, anticorps AOR_1_768154, anticorps PTRG_04183, anticorps SJAG_01680, anticorps PAAG_04978, anticorps MCYG_03290, anticorps VDBG_03742, anticorps chek1.S, anticorps Chek1, anticorps chek1
Sujet
The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.
ID gène
1111
UniProt
O14757
Pathways
Signalisation p53 , Apoptose , Cycle Cellulaire , Réparation de l'ADN
Vus récemment
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