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c-MYC anticorps (pSer62)

Name: c-MYC anticorps (pSer62)
Brand: antibodies-online
SKU: ABIN7265076
Price: 590 EUR
Availability: InStock

MYC Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated

Immunohistochemistry of paraffin-embedded Rat lung using Phospho-MYC(S62) Polyclonal Antibody at dilution of 1:100 (40x lens). (c-MYC anticorps (pSer62))

IHC (p)

Immunofluorescence analysis of U2OS cells using Phospho-MYC(S62) Polyclonal Antibody (c-MYC anticorps (pSer62))

Immunohistochemistry of paraffin-embedded Rat testis using Phospho-MYC(S62) Polyclonal Antibody at dilution of 1:100 (40x lens). (c-MYC anticorps (pSer62))

IHC (p)

Immunohistochemistry of paraffin-embedded Human lung using Phospho-MYC(S62) Polyclonal Antibody at dilution of 1:100 (40x lens). (c-MYC anticorps (pSer62))

7 images

N° du produit ABIN7265076

Fiche de données

Antigène Voir toutes c-MYC (MYC) Anticorps

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))
Épitope
58

49

46

40

24

22

17

15

15

14

10

7

7

6

6

4

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer62
Reactivité
361

164

117

16

15

13

13

13

10

10

8

7

7

6

5

4

3

3

2

2

2

1

1

1

1

1

1
Humain, Souris, Rat
Hôte
279

99

7

5

3

1
Lapin
Anticorps secondaires appropriés
Clonalité
273

120
Polyclonal
Conjugué
192

31

24

23

8

8

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

5

3

2

2

2

2

2

2

2

1

1

1

1

1

1
Cet anticorp c-MYC est non-conjugé
Application
289

139

96

80

76

59

56

28

26

21

17

14

12

11

7

4

2

1

1

1

1
Immunohistochemistry (IHC), Immunofluorescence (IF)

Attributs du produit

Phosphorylated antibody

Purification

Affinity purification

Immunogène

A phospho specific peptide corresponding to residues surrounding S62 of human MYC

Isotype

IgG

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Indications d'application

IHC 1:50-1:200 IF 1:50-1:100

Restrictions

For Research Use only
Format

Liquid

Concentration

1 mg/mL

Buffer

PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur

Sodium azide

Précaution d'utilisation

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock

-20 °C

Stockage commentaire

Store at -20°C. Avoid freeze / thaw cycles.
Antigène

c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

Autre désignation

MYC (MYC Produits)

Sujet

The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

ID gène

4609

UniProt

P01106

Pathways

Signalisation p53, Cycle Cellulaire, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, L'effet Warburg