PKC anticorps (pSer660)

N° du produit ABIN7265230

Détail du produit anti-PKC anticorps

Antigène: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Épitope: pSer660

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A phospho specific peptide corresponding to residues surrounding Ser660 of human PKC (pan) betaII

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur PKC

Antigène: PKC (PKC pan) (Protein Kinase C (pan) (PKC pan))

Autre désignation: PKC (PKC pan Produits)

Synonymes: anticorps PKC, anticorps PKCI, anticorps Prkc, anticorps Prkcc, anticorps RATPKCI, anticorps protein kinase C, gamma, anticorps Prkcg

Sujet: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes.

Poids moléculaire:

Observed_MW: 95 kDa

Calculated_MW: 59 kDa/67 kDa/74- 83 kDa

ID gène: 5578, 5579, 5580

UniProt: P17252, P05771, Q05655, Q02156, P24723, Q04759

Pathways: Positive Regulation of Response to DNA Damage Stimulus