beta Catenin anticorps (pSer33, pSer37, pThr41)
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- Antigène Voir toutes beta Catenin (CATNB) Anticorps
- beta Catenin (CATNB) (Catenin, beta (CATNB))
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Épitope
- pSer33, pSer37, pThr41
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp beta Catenin est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC)
- Attributs du produit
- Phosphorylated antibody
- Purification
- Affinity purification
- Immunogène
- A synthetic phosphorylated peptide around S33 & T41 of human beta Catenin (NP_001091679).
- Isotype
- IgG
- Top Product
- Discover our top product CATNB Anticorps primaire
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- Indications d'application
- WB 1:500-1:2000 IHC 1:50-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- Antigène
- beta Catenin (CATNB) (Catenin, beta (CATNB))
- Autre désignation
- beta-catenin (CATNB Produits)
- Synonymes
- anticorps Bfc, anticorps Catnb, anticorps Mesc, anticorps CTNNB, anticorps MRD19, anticorps armadillo, anticorps ctnnb, anticorps id:ibd2058, anticorps wu:fb73e10, anticorps wu:fi81c06, anticorps wu:fk25h01, anticorps beta-catenin, anticorps ctnnb1, anticorps CHBCAT, anticorps catenin (cadherin associated protein), beta 1, anticorps catenin beta 1, anticorps catenin (cadherin-associated protein), beta 1, anticorps catenin beta 1 L homeolog, anticorps Ctnnb1, anticorps CTNNB1, anticorps ctnnb1, anticorps ctnnb1.L
- Sujet
- The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.
- Poids moléculaire
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Observed_MW: 85 kDa
Calculated_MW: 9 kDa/85 kDa
- ID gène
- 1499
- UniProt
- P35222
- Pathways
- Peptide Hormone Metabolism
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