JAK3 anticorps (pTyr980, pTyr981)

N° du produit ABIN7265248

Détail du produit anti-JAK3 anticorps

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Épitope: pTyr980, pTyr981

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp JAK3 est non-conjugé

Application: Western Blotting (WB)

Attributs du produit: Phosphorylated antibody

Purification: Affinity purification

Immunogène: A synthetic phosphorylated peptide around Y980 of human Jak3 (NP_000206.2).

Isotype: IgG

Information d'application

Indications d'application: WB 1:500-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur JAK3

Antigène: JAK3 (Janus Kinase 3 (JAK3))

Autre désignation: Jak3 (JAK3 Produits)

Synonymes: anticorps JAK-3, anticorps JAK3_HUMAN, anticorps JAKL, anticorps L-JAK, anticorps LJAK, anticorps fae, anticorps wil, anticorps RATJAK3, anticorps JAK, anticorps Janus kinase 3, anticorps JAK3, anticorps Jak3

Sujet: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

Poids moléculaire:

Observed_MW: 110 kDa

Calculated_MW: 68 kDa/121 kDa/125 kDa

ID gène: 3718

UniProt: P52333

Pathways: Signalistation JAK/STAT, Signalisation RTK, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response