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SIGLEC8 anticorps (Extracellular Domain)

SIGLEC8 Reactivité: Humain ELISA, IP, FACS Hôte: Souris Monoclonal 7C9 unconjugated
N° du produit ABIN7013899
  • Antigène Voir toutes SIGLEC8 Anticorps
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Épitope
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    Reactivité
    • 42
    • 6
    • 2
    Humain
    Hôte
    • 32
    • 9
    • 1
    Souris
    Clonalité
    • 34
    • 8
    Monoclonal
    Conjugué
    • 22
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIGLEC8 est non-conjugé
    Application
    • 32
    • 19
    • 19
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunoprecipitation (IP), Flow Cytometry (FACS)
    Specificité
    The mouse monoclonal antibody 7C9 recognizes an extracellular epitope of SIGLEC8, an eosinophil marker, expressed e.g. in lymph nodes and spleen.
    Purification
    Purified by protein-A affinity chromatography.
    Immunogène
    Extracellular domain of human SIGLEC8 fused with Fc fragment of human IgG1
    Clone
    7C9
    Isotype
    IgG1
    Top Product
    Discover our top product SIGLEC8 Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-4 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    SIGLEC8 (Sialic Acid Binding Ig-Like Lectin 8 (SIGLEC8))
    Autre désignation
    SIGLEC8 (SIGLEC8 Produits)
    Synonymes
    anticorps SAF2, anticorps SIGLEC-8, anticorps SIGLEC8L, anticorps SIGLEC8, anticorps sialic acid binding Ig like lectin 8, anticorps sialic acid-binding Ig-like lectin 8, anticorps SIGLEC8, anticorps LOC506364
    Sujet
    Sialic acid binding Ig like lectin 8,SIGLEC8 is a sialic acid binding lectin similar to CD33. In its cytoplasmic comain it contains an immunoreceptor tyrosine-based inhibitory motif (ITIM), and a motive similar to a binding site for SLAM-associated protein. SIGLEC8 is expressed e.g. in lymph nodes and spleen. It is an eosinophil marker, although it can be found also on the surface of mast cells. Crosslinking of SIGLEC8 leads to apoptosis. Soluble form of SIGLEC8 can be foud in human serum, especially in case of eosinophil-associated diseases.,SAF2
    ID gène
    27181
    UniProt
    Q9NYZ4
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