CD51/CD61 anticorps
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- Antigène Voir toutes CD51/CD61 (ITGAV/ITGB3) Anticorps
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
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Reactivité
- Humain, Poulet
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD51/CD61 est non-conjugé
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Application
- Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- The mouse monoclonal antibody 23C6 recognizes an extracellular epitope on CD51/CD61 complex, that is expressed mainly on human osteoclasts, but also e.g. on placenta, or melanoma cell lines. The epitope is native and sensitive to fixation. In chicken this antibody can be used to selectively identify the thrombocytes.
- Aucune reactivité croisée
- Boeuf (Vache), Porc, Lapin
- Purification
- Purified by protein-A affinity chromatography.
- Immunogène
- A cell suspension containing osteoclasts from osteoclastomas
- Clone
- 23C6
- Isotype
- IgG1
- Top Product
- Discover our top product ITGAV/ITGB3 Anticorps primaire
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- Indications d'application
- Flow cytometry: Recommended dilution: 2-6 μg/mL
- Restrictions
- For Research Use only
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- Concentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Antigène
- CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))
- Autre désignation
- CD51/CD61 (ITGAV/ITGB3 Produits)
- Synonymes
- anticorps CD51, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps integrin subunit alpha V, anticorps ITGAV
- Sujet
- CD51/CD61 (integrin alpha5beta3), also known as osteoclast functional antigen, serves as a vitronectin receptor, and binds also to fibronectin, fibrinogen, thrombospondin, osteopontin, collagen, and von Willebrand factor. Expression of this antigen increases with melanoma progression. In healthy individuals CD51/CD61 is expressed mainly on osteoclasts, placenta, and endothelial cells, at lower levels on platelets and macrophages.,VNRA, MSK8, ITGB3, ITGAV, Integrin alpha5beta3, OFA, VR
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