ZYX anticorps (pSer142, pSer143)

N° du produit ABIN701710

Détail du produit anti-ZYX anticorps

Antigène: ZYX (Zyxin (ZYX))

Épitope: pSer142, pSer143

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZYX est non-conjugé

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic phosphopeptide derived from human Zyxin around the phosphorylation site of Ser142/Ser143

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur ZYX

Antigène: ZYX (Zyxin (ZYX))

Autre désignation: Zyxin (ZYX Produits)

Synonymes: anticorps BcDNA:LD06023, anticorps CG32018, anticorps DLim-1, anticorps DmLIM-1, anticorps Dmel\\CG32018, anticorps Lim102EF, anticorps ZYX102, anticorps Zyx102, anticorps Zyx102EF, anticorps lim, anticorps zyx102, anticorps zyxin, anticorps zgc:171680, anticorps ZYX, anticorps zyx, anticorps MGC145270, anticorps ESP-2, anticorps HED-2, anticorps 9530098H06Rik, anticorps R75157, anticorps Zyxin, anticorps zyxin, anticorps zyxin S homeolog, anticorps zyx-1, anticorps Zyx, anticorps zyx, anticorps ZYX, anticorps EDI_201420, anticorps zyx.S

Sujet:

Synonyms: ESP 2, ESP2, HED 2, HED2, ZYX, ZYX protein, Zyxin 2, Zyxin2, ZYX_HUMAN.

Background: Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Jul 2008].

ID gène: 7791