OGG1 anticorps (AA 151-250)

N° du produit ABIN702655

Détail du produit anti-OGG1 anticorps

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Épitope: AA 151-250

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OGG1 est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Réactivité croisée: Humain, Souris, Rat

Homologie: Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human OGG1/8 hydroxyguanine DNA glycosylase

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-OGG1 (ABIN702655)

Cogoi, Ferino, Miglietta, Pedersen, Xodo: "The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription." dans: Nucleic acids research, Vol. 46, Issue 2, pp. 661-676, (2017) (PubMed).

Détails sur OGG1

Antigène: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Autre désignation: OGG1 (OGG1 Produits)

Synonymes: anticorps OGG1, anticorps zgc:158858, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps ARABIDOPSIS 8-OXOGUANINE-DNA GLYCOSYLASE 1, anticorps ATOGG1, anticorps F8K7.14, anticorps F8K7_14, anticorps 19.m02329, anticorps DDBDRAFT_0184479, anticorps DDBDRAFT_0233024, anticorps DDB_0184479, anticorps DDB_0233024, anticorps ogg1, anticorps Tb04.1H19.930, anticorps HMMH, anticorps HOGG1, anticorps MUTM, anticorps OGH1, anticorps Mmh, anticorps 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA glycosylase L homeolog, anticorps 8-oxoguanine-DNA glycosylase 1, anticorps 8-OXOGUANINE DNA GLYCOSYLASE, anticorps putative 8-oxoguanine DNA glycosylase, anticorps 8-oxoguanine DNA-glycosylase, anticorps N-glycosylase/DNA lyase OGG1, anticorps 8-oxoguanine DNA-glycosylase 1, anticorps OGG1, anticorps ogg1.L, anticorps ogg1, anticorps ECU08_0770, anticorps CA_C2707, anticorps BBOV_I004290, anticorps Smp_074010.1, anticorps LOC9329243, anticorps Tb927.4.2480, anticorps Ogg1

Sujet:

Synonyms: 8 hydroxyguanine DNA glycosylase, 8 oxoguanine DNA glycosylase 1, 8-oxoguanine DNA glycosylase, AP lyase, DNA apurinic or apyrimidinic site lyase, DNA lyase, DNA-apurinic or apyrimidinic site lyase, HMMH, HOGG 1, HOGG1, MMH, MUTM, N-glycosylase, Ogg 1, OGH 1, OGH1, OGG1_HUMAN.

Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008].

ID gène: 4968

Pathways: Réparation de l'ADN