Recombinant G Protein-Coupled Receptor 119 anticorps

N° du produit ABIN7072310

Détail du produit anti-G Protein-Coupled Receptor 119 anticorps

Antigène: G Protein-Coupled Receptor 119 (GPR119)

Type d'anticorp: Recombinant Antibody

Reactivité: Humain, Souris, Rat, Chien

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp G Protein-Coupled Receptor 119 est non-conjugé

Application: ELISA, Immunofluorescence (IF), Blocking Peptide (BP)

Fonction: Anti-Glucose-dependent insulinotropic Receptor [Gipg013], Mouse IgG2a, lambda

Specificité: The original has a Ki value of 7 nM and a Kd value of 6.8 nM for human GIPr.

Réactivité croisée: Chien, Souris, Rat

Attributs du produit:

Original Species of Ab: Mouse

Original Format of Ab: scFv

Purification: Protein A affinity purified

Immunogène: Human GIPr.

Clone: Gipg013

Isotype: IgG2a lambda

Information d'application

Indications d'application: This antibody binds to GIPr, a GPCR expressed on pancreatic beta-cells, where activation leads to the release of insulin. Endogeonous ligands for the receptor include oleylethanolamide and lysophosphatidylcholine. The antibody acts as a competitive antagonist. In rat islets, the antibody inhibits GIP-induced secretion of insulin by up to 81 % .

Commentaires:

This full-length, reformatted mouse antibody was made using the variable domain sequences of the original Mouse scFv format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur G Protein-Coupled Receptor 119

Antigène: G Protein-Coupled Receptor 119 (GPR119)

Autre désignation: Glucose-dependent insulinotropic Receptor (GPR119 Produits)

Sujet: GIPr

UniProt: Q8TDV5

Pathways: Hormone Transport, Peptide Hormone Metabolism