Recombinant CD96 anticorps

N° du produit ABIN7072566

Détail du produit anti-CD96 anticorps

Antigène: CD96

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD96 est non-conjugé

Application: Flow Cytometry (FACS), Blocking Peptide (BP)

Fonction: Anti-CD96 [6A6], Rat IgG2a, lambda

Specificité: This antibody is specific for murine CD96, and recognises an epitope in the first Ig domain.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunising rats with murine CD96.

Clone: 6A6

Isotype: IgG2a lambda

Information d'application

Indications d'application: This antibody blocks murine CD96-CD155 interaction, and has been shown to bind to the first Ig domain of CD96 and compete with CD155 binding (Roman Aguilera et al, 2018). This antibody displays significant anti-metastatic activity in four experimental lung metastases models and one spontaneous tumour metastasis model (Roman Aguilera et al, 2018), with a potency greater than the anti-CD96 monoclonal antibodies 3.3 and 8B10. The binding specificity of this antibody has been determined in flow cytometric analysis of HEK-293 cells transfected with a range of CD96 Ig domain chimeric constructs (Roman Aguilera et al, 2018).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CD96

Antigène: CD96

Autre désignation: CD96 (CD96 Produits)

Sujet: TACTILE, T-cell surface protein tactile, T cell-activated increased late expression protein

UniProt: Q3U0X8