Recombinant CCR9 anticorps (N-Term)

N° du produit ABIN7072662

Détail du produit anti-CCR9 anticorps

Antigène: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Type d'anticorp: Recombinant Antibody

Épitope: N-Term

Reactivité: Souris

Hôte: Lapin

Clonalité: Chimeric

Conjugué: Cet anticorp CCR9 est non-conjugé

Application: Flow Cytometry (FACS), Neutralization (Neut)

Fonction: Anti-CCR9 [9B1], Rabbit IgG, kappa

Specificité: 9B1 antibody recognizes CCR9 at the N-terminus. CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells.

Attributs du produit:

Original Species of Ab: Rat

Original Format of Ab: IgG2a

Purification: Protein A affinity purified

Immunogène: This antibody was raised by immunizing rats with KLH-conjugated linear peptide corresponding to the N-terminus of mouse CCR9.

Clone: 9B1

Isotype: IgG kappa

Information d'application

Indications d'application: This antibody is recommended for the detection and analysis of CCR9 via flow cytometry (Farazuddin et al., 2019). Furthermore, it was demonstrated that this 9B1 antibody was capable of neutralizing CCR9 function, as it inhibited CCL25-induced calcium mobilization in L1.2-CCR9 cells (Rivera-Nieves et al., 2006).

Commentaires:

This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur CCR9

Antigène: CCR9 (Chemokine (C-C Motif) Receptor 9 (CCR9))

Autre désignation: CCR9 (CCR9 Produits)

Sujet: CD199, C-C chemokine receptor type 9, C-C CKR-9, CC-CKR-9, CCR-9, G-protein coupled receptor 28, GPR-9-6, CDw199, 9B-1

UniProt: Q9WUT7