Seladin 1 anticorps
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- Antigène Voir toutes Seladin 1 (DHCR24) Anticorps
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Seladin 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse Seladin 1
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- Indications d'application
- WB (H) 1:500-1:1000, IHC/IF (M,R) 1:600-1:3000/1:500-1:1300
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
- Autre désignation
- Seladin 1 (DHCR24 Produits)
- Synonymes
- anticorps MGC82737, anticorps zgc:101638, anticorps DCE, anticorps Nbla03646, anticorps SELADIN1, anticorps seladin-1, anticorps 2310076D10Rik, anticorps 5830417J06Rik, anticorps mKIAA0018, anticorps 24-dehydrocholesterol reductase, anticorps 24-dehydrocholesterol reductase S homeolog, anticorps delta(24)-sterol reductase, anticorps DHCR24, anticorps dhcr24.S, anticorps dhcr24, anticorps LOC5575872, anticorps CpipJ_CPIJ000670, anticorps Dhcr24
- Sujet
- The Seladin 1 encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis.Missense mutations in this gene have been associated with desmosterolosis.
- Poids moléculaire
- 60 kDa
- ID gène
- 74754
- NCBI Accession
- NP_444502
- UniProt
- Q8VCH6
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