ABCC6 anticorps

N° du produit ABIN7073149

Détail du produit anti-ABCC6 anticorps

Antigène: ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABCC6 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse MRP6/ARA

Information d'application

Indications d'application: IHC/IF (M,R) 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ABCC6

Antigène: ABCC6 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 6 (ABCC6))

Autre désignation: MRP6/ARA (ABCC6 Produits)

Synonymes: anticorps ABC34, anticorps ARA, anticorps EST349056, anticorps GACI2, anticorps MLP1, anticorps MOAT-E, anticorps MOATE, anticorps MRP6, anticorps PXE, anticorps PXE1, anticorps URG7, anticorps Abcc1b, anticorps DCC, anticorps Dyscalc1, anticorps Mrp6, anticorps dyscalc, anticorps ATP binding cassette subfamily C member 6, anticorps ATP-binding cassette, sub-family C (CFTR/MRP), member 6, anticorps ABCC6, anticorps Abcc6

Sujet: The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2). 27848-1-AP detects two isoforms of ABCC6 protein around 165 kDa and 96 kDa in SDS-PAGE.

ID gène: 27421

NCBI Accession: NP_061265

UniProt: Q9R1S7