CD5L anticorps

N° du produit ABIN7073398

Détail du produit anti-CD5L anticorps

Antigène: CD5L (CD5 Molecule-Like (CD5L))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD5L est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse CD5L/CT-2

Information d'application

Indications d'application: WB (R) 1:700-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CD5L

Antigène: CD5L (CD5 Molecule-Like (CD5L))

Autre désignation: CD5L/CT-2 (CD5L Produits)

Sujet: CD5L is a member of the scavenger receptor cysteine-rich domain superfamily (SRCR-SF) initially identified as an inducible cell surface ligand of CD5. It was shown that CD5L functions in the thymus as the inducer of resistance to apoptosis within CD4+/CD8+ thymocytes and as the supporter of the viability of these cells before thymic selection. CD5L was also shown to support macrophage survival and enhance their phagocytic function. More recent experiments using recombinant CD5L significantly inhibited apoptosis of NKT and T cells obtained from C. parvum-stimulated livers in vitro, suggesting that CD5L functions to induce resistance to apoptosis in these cells and supports host defense against inflammation during infection. Expressed in spleen, lymph node, thymus, bone marrow, and fetal liver, but not in non-lymphoid tissues.

Poids moléculaire: 46 kDa

ID gène: 11801

NCBI Accession: NP_033820

UniProt: Q9QWK4