CD35 anticorps

N° du produit ABIN7073563

Détail du produit anti-CD35 anticorps

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD35 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Souris, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Human CD35

Information d'application

Indications d'application: WB (M,R) 1:500-1:1000, IHC/IF (H,R) 1:650-1:1300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur CD35

Antigène: CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))

Autre désignation: CD35 (CR1 Produits)

Synonymes: anticorps C3BR, anticorps C4BR, anticorps CD35, anticorps KN, anticorps C3DR, anticorps CD21, anticorps Cr-1, anticorps Cr-2, anticorps Cr1, anticorps CR1-L, anticorps CR2, anticorps CR1, anticorps complement C3b/C4b receptor 1 (Knops blood group), anticorps complement receptor 2, anticorps complement component (3d/Epstein Barr virus) receptor 2, anticorps complement receptor type 1, anticorps CR1, anticorps Cr2, anticorps CR2, anticorps LOC718120

Sujet: This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in its gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus and sarcoidosis.

Poids moléculaire: 224 kDa

ID gène: 1378

NCBI Accession: NP_000564

UniProt: P17927

Pathways: Système du Complément, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity