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CRTC1 anticorps
CRTC1
Reactivité: Souris, Rat
IHC, IF
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN7073590
Détail du produit anti-CRTC1 anticorps
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Antigène
Voir toutes CRTC1 Anticorps
CRTC1
(CREB Regulated Transcription Coactivator 1 (CRTC1))
Reactivité
Toutes les réactivités sur CRTC1 Anticorps
Souris, Rat
Hôte
Toutes les hôtes sur CRTC1 Anticorps
Lapin
Clonalité
Toutes les clonalités sur CRTC1 Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers CRTC1 Anticorps
Cet anticorp CRTC1 est non-conjugé
Application
Tous les applications à travers CRTC1 Anticorps.
Immunohistochemistry (IHC), Immunofluorescence (IF)
Réactivité croisée
Rat
Purification
Affinity purification
Immunogène
KLH conjugated Synthetic peptide corresponding to Mouse TORC1
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Alternatives
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Information d'application
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Indications d'application
IHC/IF (M,R) 1:400-1:800
Restrictions
For Research Use only
Stockage
(cache)
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Détails sur CRTC1
(cache)
Antigène
CRTC1
(CREB Regulated Transcription Coactivator 1 (CRTC1))
Autre désignation
TORC1 (CRTC1 Produits )
Synonymes
anticorps MECT1, anticorps TORC-1, anticorps TORC1, anticorps WAMTP1, anticorps AI413414, anticorps Mect1, anticorps R74955, anticorps mKIAA0616, anticorps CRTC1, anticorps crtc1, anticorps fc68c05, anticorps pde4cb, anticorps si:ch211-255d18.1, anticorps si:ch211-255d18.8, anticorps wu:fc68c05, anticorps CREB regulated transcription coactivator 1, anticorps CREB regulated transcription coactivator 1b, anticorps CRTC1, anticorps Crtc1, anticorps crtc1, anticorps crtc1b
Sujet
CRTC1, also named as MECT1, TORC1, and WAMTP1, belongs to the TORC family. It is a transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. CRTC1 acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. It enhances the interaction of CREB1 with TAF4. CRTC1 regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. It is a potent coactivator of PGC1alpha and inducer of mitochondrial biogenesis in muscle cells.
ID gène
382056
NCBI Accession
NP_001004062
UniProt
Q68ED7
Vus récemment
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