DOCK2 anticorps

N° du produit ABIN7073706

Détail du produit anti-DOCK2 anticorps

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DOCK2 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse DOCK2

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur DOCK2

Antigène: DOCK2 (Dedicator of Cytokinesis 2 (DOCK2))

Autre désignation: DOCK2 (DOCK2 Produits)

Synonymes: anticorps AI662014, anticorps AW122239, anticorps CED-5, anticorps Hch, anticorps MBC, anticorps dedicator of cytokinesis 2, anticorps dedicator of cyto-kinesis 2, anticorps DOCK2, anticorps dock2, anticorps Dock2

Sujet: The DOCK2 gene encodes dedicator of cytokinesis 2 (DOCK 2), a hematopoietic cell-specific CDM family protein that is indispensable for lymphocyte chemotaxis. DOCK 2 participates in the cytoskeletal rearrangements that are required for lymphocyte migration in response of chemokines. DOCK 2 may also participate in IL-2 transcriptional activation through the activation of Rac 2. DOCK 2 contains one DHR-1 (CZH-1) domain, one DHR-2 (CZH-2) domain and one SH3 domain. The DHR-2 domain is a putative GEF activity mediator. The DOCK 2 protein also co-localizes with F-Actin, and demonstrates expression in several human tissues, with the highest levels observed in peripheral blood leukocytes, thymus, spleen and liver.

Poids moléculaire: 220 kDa

ID gène: 94176

NCBI Accession: NP_203538

UniProt: Q8C3J5