NEIL1 anticorps

N° du produit ABIN7073820

Détail du produit anti-NEIL1 anticorps

Antigène: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NEIL1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse NEIL1

Information d'application

Indications d'application: WB (M,R) 1:800-1:1600, IHC/IF (H,M,R) 1:1200-1:3000/1:300-1:600

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur NEIL1

Antigène: NEIL1 (Endonuclease VIII-Like 1 (NEIL1))

Autre désignation: NEIL1 (NEIL1 Produits)

Sujet: NEIL1, also named as NEH1 and FPG1, belongs to the FPG family. It is involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. NEIL1 acts as DNA glycosylase that recognizes and removes damaged bases. It has a preference for oxidized pyrimidines, such as thymine glycol, formamidopyrimidine (Fapy) and 5-hydroxyuracil. NEIL1 has marginal activity towards 8-oxoguanine. It has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand.

Poids moléculaire: 44 kDa

ID gène: 72774

NCBI Accession: NP_082623

UniProt: Q8K4Q6

Pathways: Réparation de l'ADN