EIF3D anticorps

N° du produit ABIN7073884

Détail du produit anti-EIF3D anticorps

Antigène: EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF3D est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse EIF3D

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur EIF3D

Antigène: EIF3D (Eukaryotic Translation Initiation Factor 3, Subunit D (EIF3D))

Autre désignation: EIF3D (EIF3D Produits)

Sujet: EIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.

Poids moléculaire: 64 kDa

ID gène: 55944

NCBI Accession: NP_061219

UniProt: O70194

Pathways: Ribonucleoprotein Complex Subunit Organization