Foxk1 anticorps

N° du produit ABIN7073970

Détail du produit anti-Foxk1 anticorps

Antigène: Foxk1 (Forkhead Box K1 (Foxk1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Foxk1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse FOXK1/MNF

Information d'application

Indications d'application: WB (H) 1:500-1:1000, IHC/IF (H,M,R) 1:1000-1:2000/1:650-1:1300

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur Foxk1

Antigène: Foxk1 (Forkhead Box K1 (Foxk1))

Autre désignation: FOXK1/MNF (Foxk1 Produits)

Sujet: The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. In skeletal muscles, undifferentiated myogenic stem cells (satellite cells) can mobilize to regenerate myofibers in response to injury. FOXK1 is expressed in these cells and regulates cell cycle progression through an interaction with its downstream target the cyclin-dependent kinase inhibitor p21 (CIP). Loss of FOXK1 in mice results in growth retardation and a severe impairment in skeletal muscle regeneration following injury. FOXK1 also shows expression in immature tissues of brain, eye, heart, lung and thymus.

Poids moléculaire: 97 kDa

ID gène: 17425

NCBI Accession: NP_951031

UniProt: P42128