HECTD1 anticorps
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- Antigène Voir toutes HECTD1 Anticorps
- HECTD1 (HECT Domain Containing 1 (HECTD1))
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp HECTD1 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse HECTD1
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- Indications d'application
- IHC/IF (R) 1:1000-1:2000/1:1000-1:2000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- HECTD1 (HECT Domain Containing 1 (HECTD1))
- Autre désignation
- HECTD1 (HECTD1 Produits)
- Synonymes
- anticorps RGD1561653, anticorps HECTD1, anticorps hectd1, anticorps MGC172681, anticorps A630086P08Rik, anticorps AI844876, anticorps b2b327Clo, anticorps opm, anticorps HECT domain E3 ubiquitin protein ligase 1, anticorps HECT domain containing E3 ubiquitin protein ligase 1, anticorps Hectd1, anticorps HECTD1, anticorps hectd1
- Sujet
- HECTD1 (E3 ubiquitin-protein ligase, which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates . Mediates 'Lys-63'-linked polyubiquitination of HSP90AA1 which leads to its intracellular localization and reduced secretion . Negatively regulating HSP90AA1 secretion in cranial mesenchyme cells impairs their emigration and is consequently essential for the correct development of the cranial neural folds and neural tube closure.It is also involved in sporadic Parkinson's disease.
- UniProt
- Q69ZR2
- Pathways
- Tube Formation, SARS-CoV-2 Protein Interactome, Phosphorylation & l'infection par le SRAS-CoV-2
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