ISR-alpha anticorps

N° du produit ABIN7074298

Détail du produit anti-ISR-alpha anticorps

Antigène: ISR-alpha (Insulin Receptor alpha (ISR-alpha))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ISR-alpha est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse Insulin Receptor alpha

Information d'application

Indications d'application: IHC: 1: 3000-1: 6000
Human, Mouse, Rat: Human, Mouse, Rat
Positive Tissue: endometrial cancer, esophagus cancer, uterus,small intestine

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ISR-alpha

Antigène: ISR-alpha (Insulin Receptor alpha (ISR-alpha))

Autre désignation: Insulin Receptor alpha (ISR-alpha Produits)

Synonymes: anticorps CD220, anticorps HHF5, anticorps insulin receptor, anticorps INSR

Sujet: This gene encodes a member of the receptor tyrosine kinase family of proteins. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited severe insulin resistance syndromes including type A insulin resistance syndrome, Donohue syndrome and Rabson-Mendenhall syndrome. Alternative splicing results in multiple transcript variants.

ID gène: 16337

UniProt: P15208