CD51 anticorps
-
- Antigène Voir toutes CD51 (ITGAV) Anticorps
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
-
Reactivité
- Humain, Souris, Rat
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp CD51 est non-conjugé
-
Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Rat
- Purification
- Affinity purification
- Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse Integrin alpha-V
- Top Product
- Discover our top product ITGAV Anticorps primaire
-
-
- Indications d'application
- IHC/IF (H,M,R) 1:500-1:2000/1:500-1:1000
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
-
- Antigène
- CD51 (ITGAV) (Integrin alpha V (ITGAV))
- Autre désignation
- Integrin alpha V (ITGAV Produits)
- Synonymes
- anticorps 1110004F14Rik, anticorps 2610028E01Rik, anticorps CD51, anticorps D430040G12Rik, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps Cd51, anticorps integrin subunit alpha V, anticorps integrin alpha V, anticorps ITGAV, anticorps Itgav
- Sujet
- The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling . ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling . ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1.
- ID gène
- 16410
- NCBI Accession
- NP_032428
- UniProt
- P43406
- Pathways
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
-