MRPL12 anticorps

N° du produit ABIN7074638

Détail du produit anti-MRPL12 anticorps

Antigène: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MRPL12 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Souris, Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Human MRPL12

Information d'application

Indications d'application: WB (M,R) 1: 500-1: 1000, IHC/IF (H) 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MRPL12

Antigène: MRPL12 (Mitochondrial Ribosomal Protein L12 (MRPL12))

Autre désignation: MRPL12 (MRPL12 Produits)

Synonymes: anticorps 5c5-2, anticorps L12mt, anticorps MRP-L31/34, anticorps MRPL7, anticorps MRPL7/L12, anticorps RPML12, anticorps GB14723, anticorps MRPL12, anticorps 0610034O11Rik, anticorps 1500031N16Rik, anticorps MRP-L12, anticorps Rpml12, anticorps Rpm12, anticorps im:6893415, anticorps zgc:112445, anticorps mrpl12, anticorps mitochondrial ribosomal protein L12, anticorps 39S ribosomal protein L12, mitochondrial, anticorps mitochondrial nucleoid protein, anticorps mitochondrial ribosomal protein L12 L homeolog, anticorps MRPL12, anticorps LOC409926, anticorps CAALFM_C207190CA, anticorps Mrpl12, anticorps mrpl12, anticorps mrpl12.L

Sujet: MRPL12 is a component of the 39S subunit of mammalian mitochondrial ribosomes, and is encoded by a nuclear gene. The protein forms a homodimer, localizes predominantly to mitochondria and binds to the large mitochondrial ribosomal subunit. It is required for CycD/Cdk4- induced cell growth. In addition, forming a ribosomal stalk with MRPL7, MRPL12 is required for the recruitment of translation elongation factors Tu and G to the large ribosomal subunit . It also a part of a novel regulatory mechanism that coordinates mitochondrial transcription with translation and/or ribosome biogenesis during human mitochondrial gene expression.

Poids moléculaire: 21 kDa

ID gène: 56282

NCBI Accession: NP_081480

UniProt: Q9DB15