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MAP3K3 anticorps

MAP3K3 Reactivité: Humain, Souris, Rat WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7074682
  • Antigène Voir toutes MAP3K3 Anticorps
    MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
    Reactivité
    • 34
    • 31
    • 16
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 42
    • 4
    Lapin
    Clonalité
    • 35
    • 11
    Polyclonal
    Conjugué
    • 29
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MAP3K3 est non-conjugé
    Application
    • 36
    • 20
    • 9
    • 8
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    Recombinant protein corresponding to Mouse MEKK3
    Top Product
    Discover our top product MAP3K3 Anticorps primaire
  • Indications d'application
    WB (H,M,R) 1: 800-1: 1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    MAP3K3 (Mitogen-Activated Protein Kinase Kinase Kinase 3 (MAP3K3))
    Autre désignation
    MEKK3 (MAP3K3 Produits)
    Synonymes
    anticorps MAPKKK3, anticorps MEKK3, anticorps AW548911, anticorps Mekk3, anticorps mKIAA4031, anticorps mitogen activated protein kinase kinase kinase 3, anticorps mitogen-activated protein kinase kinase kinase 3, anticorps Map3k3, anticorps MAP3K3, anticorps map3k3
    Sujet
    The mitogen-activated protein/ERK kinase kinase 3 (MEKK3) is a member of a family of MEKK/Ste11 serine/threonine protein kinases. One function of MEKK3 is to serve as an upstream regulatory kinase in the mitogen activated protein kinase cascade, however, it also plays a critical role in other signaling pathways. MEKK3 regulates several important functions including cell survival and proliferation. It is ubiquitously expressed in multiple tissues and has been found in complexes with scaffold proteins and other kinases.Cerebral cavernous malformations (CCMs) complex regulation of MEKK3 is essential during vertebrate heart development. MEKK3 signalling and KLF2/4 may be targeted to develop new CCM therapeutics.
    Poids moléculaire
    78 kDa
    ID gène
    26406
    NCBI Accession
    NP_036077
    UniProt
    Q61084
    Pathways
    Signalisation MAPK
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