MLF1 anticorps

N° du produit ABIN7074712

Détail du produit anti-MLF1 anticorps

Antigène: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MLF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse Myeloid leukemia factor 1

Information d'application

Indications d'application: WB (M,R) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur MLF1

Antigène: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Autre désignation: Myeloid leukemia factor 1 (MLF1 Produits)

Synonymes: anticorps MLF1, anticorps HLS7, anticorps myeloid leukemia factor 1, anticorps myeloid leukemia factor 1 L homeolog, anticorps MLF1, anticorps mlf1.L, anticorps mlf1, anticorps Mlf1

Sujet: Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Poids moléculaire: 31 kDa

ID gène: 17349

NCBI Accession: NP_034931

UniProt: Q9QWV4