ASAH2 anticorps

N° du produit ABIN7074749

Détail du produit anti-ASAH2 anticorps

Antigène: ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASAH2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse ASAH2

Information d'application

Indications d'application: IHC/IF (M) 1:2100-1:4200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ASAH2

Antigène: ASAH2 (N-Acylsphingosine Amidohydrolase (Non-Lysosomal Ceramidase) 2 (ASAH2))

Autre désignation: ASAH2 (ASAH2 Produits)

Synonymes: anticorps BCDase, anticorps HNAC1, anticorps LCDase, anticorps N-CDase, anticorps NCDase, anticorps AI585898, anticorps N-acylsphingosine amidohydrolase 2, anticorps ASAH2, anticorps Asah2

Sujet: Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid at an optimal pH of 6.5-8.5. Acts as a key regulator of sphingolipid signaling metabolites by generating sphingosine at the cell surface. Acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine, a precursor of the antiapoptotic factor sphingosine 1-phosphate. Probably involved in the digestion of dietary sphingolipids in intestine by acting as a key enzyme for the catabolism of dietary sphingolipids and regulating the levels of bioactive sphingolipid metabolites in the intestinal tract.

ID gène: 54447

UniProt: Q9JHE3