NOS1AP anticorps

N° du produit ABIN7074844

Détail du produit anti-NOS1AP anticorps

Antigène: NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOS1AP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain, Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse CAPON/NOS1AP

Information d'application

Indications d'application: WB (H,M,R) 1:500-1:1000, IHC/IF (M,R) 1:2000-1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur NOS1AP

Antigène: NOS1AP (Nitric Oxide Synthase 1 (Neuronal) Adaptor Protein (NOS1AP))

Autre désignation: CAPON/NOS1AP (NOS1AP Produits)

Synonymes: anticorps MGC78853, anticorps Capon, anticorps MGC145362, anticorps 6330408P19Rik, anticorps CAPON, anticorps nitric oxide synthase 1 adaptor protein, anticorps nitric oxide synthase 1 adaptor protein L homeolog, anticorps nitric oxide synthase 1 (neuronal) adaptor protein a, anticorps carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein, anticorps chromosome 18 C1orf226 homolog, anticorps nitric oxide synthase 1 (neuronal) adaptor protein, anticorps NOS1AP, anticorps nos1ap.L, anticorps nos1apa, anticorps LOC609484, anticorps nos1ap, anticorps LOC100058633, anticorps C18H1orf226, anticorps Nos1ap

Sujet: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels.

Poids moléculaire: 56 kDa

ID gène: 70729

NCBI Accession: NP_001103455

UniProt: Q9D3A8