NLRP1 anticorps
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- Antigène Voir toutes NLRP1 Anticorps
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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Reactivité
- Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp NLRP1 est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse NLRP1
- Top Product
- Discover our top product NLRP1 Anticorps primaire
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- Indications d'application
- IHC/IF (M,R) 1:500-1:2000/1:250-1:500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
- Autre désignation
- NLRP1 (NLRP1 Produits)
- Synonymes
- anticorps CARD7, anticorps CIDED, anticorps CLR17.1, anticorps DEFCAP, anticorps DEFCAP-L/S, anticorps NAC, anticorps NALP1, anticorps PP1044, anticorps SLEV1, anticorps VAMAS1, anticorps NLR family pyrin domain containing 1, anticorps NLRP1, anticorps Nlrp1
- Sujet
- NACHT, LRR and PYD domains-containing protein 1 is a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. The NLRP1 protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
- ID gène
- 195046
- NCBI Accession
- NP_001004142
- UniProt
- Q2LKU9
- Pathways
- Positive Regulation of Endopeptidase Activity, Inflammasome
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