O3FAR1 anticorps

N° du produit ABIN7074942

Détail du produit anti-O3FAR1 anticorps

Antigène: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp O3FAR1 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: KLH conjugated Synthetic peptide corresponding to Mouse GPR120

Information d'application

Indications d'application: IHC/IF (M,R) 1:1000-1:2000/1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur O3FAR1

Antigène: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Autre désignation: GPCR GPR120 (O3FAR1 Produits)

Synonymes: anticorps BMIQ10, anticorps GPR120, anticorps GPR129, anticorps GT01, anticorps O3FAR1, anticorps PGR4, anticorps AI552415, anticorps Gpr120, anticorps Gpr129, anticorps KPG_013, anticorps O3far1, anticorps Pgr4, anticorps free fatty acid receptor 4, anticorps phosphodiesterase 6C, anticorps FFAR4, anticorps Ffar4, anticorps PDE6C

Sujet: GPR120, a member of the rhodopsin family of G protein-coupled receptors (GPCRs), is a 377 amino acid protein which is expressed in the intestine. GPR120 is a receptor for unsaturated long-chain FFAs (free fatty acids). FFAs act as signaling molecules and are an important energy source. They also employ various physiological responses through their GPCRs. One such response occurs when dietary FFAs stimulate GPR120. This stimulation promotes the secretion of glucagon-like peptide 1 (GLP-1) in vivo and in vitro. GLP-1 belongs to the class of molecules known as the incretins, which are associated with insulin secreted from the pancreas as a result of food intake. GLP-1 also inhibits glucagon and gastric acid secretion and gastric emptying. Consequently, the role of GPR120 in the secretion of GLP-1 is critical in the treatment of diabetes.

ID gène: 107221

NCBI Accession: NP_861413

UniProt: Q7TMA4

Pathways: Hormone Transport