PNN anticorps
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- Antigène Voir toutes PNN Anticorps
- PNN (Pinin, Desmosome Associated Protein (PNN))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PNN est non-conjugé
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Application
- Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Rat
- Purification
- Affinity purification
- Immunogène
- KLH conjugated Synthetic peptide corresponding to Mouse PNN/DRSP
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- Indications d'application
- IHC/IF (H,M,R) 1:600-1:1200/1:400-1:800
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- PNN (Pinin, Desmosome Associated Protein (PNN))
- Autre désignation
- PNN/DRSP (PNN Produits)
- Synonymes
- anticorps DRS, anticorps DRSP, anticorps SDK3, anticorps memA, anticorps wu:fb24d03, anticorps pnn, anticorps MGC88923, anticorps PNN, anticorps AU045199, anticorps D12Ertd512e, anticorps CG8383, anticorps Dmel\\CG8383, anticorps dPnn, anticorps pinin, desmosome associated protein, anticorps pinin, anticorps Pinin, anticorps PNN, anticorps Pnn, anticorps pnn, anticorps LOC100380709
- Sujet
- PNN, also named as DRS or 140 kDa nuclear and cell adhesion-related phosphoprotein, is a 717 amino acid protein, which belongs to the pinin family. PNN localizes in the plasma membrane and is expressed in placenta, lung, liver, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon, heart, epidermis, esophagus, brain and smooth and skeletal muscle. PNN is expressed strongly in melanoma metastasis lesions and advanced primary tumors. PNN as a transcriptional activator binds to the E-box 1 core sequence of the E-cadherin promoter gene. PNN is involved in the establishment and maintenance of epithelia cell-cell adhesion. PNN is a potential tumor suppressor for renal cell carcinoma.
- ID gène
- 18949
- NCBI Accession
- NP_032917
- UniProt
- O35691
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