PARN anticorps

N° du produit ABIN7075117

Détail du produit anti-PARN anticorps

Antigène: PARN (Poly A Specific Ribonuclease (PARN))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PARN est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Humain

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse PARN

Information d'application

Indications d'application: WB (H,M) 1:500-1:1000, IHC/IF (H) 1:900-1:1800

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur PARN

Antigène: PARN (Poly A Specific Ribonuclease (PARN))

Autre désignation: PARN (PARN Produits)

Synonymes: anticorps parn-A, anticorps xparn, anticorps DAN, anticorps RGD1565449, anticorps zgc:56067, anticorps 1200003I18Rik, anticorps poly(A)-specific ribonuclease L homeolog, anticorps poly(A)-specific ribonuclease, anticorps poly(A)-specific ribonuclease (deadenylation nuclease), anticorps parn.L, anticorps PARN, anticorps Parn, anticorps parn

Sujet: The protein encoded by this gene is a 3'-exoribonuclease, with similarity to the RNase D family of 3'-exonucleases. It prefers poly(A) as the substrate, hence, efficiently degrades poly(A) tails of mRNAs. Exonucleolytic degradation of the poly(A) tail is often the first step in the decay of eukaryotic mRNAs. This protein is also involved in silencing of certain maternal mRNAs during oocyte maturation and early embryonic development, as well as in nonsense-mediated decay (NMD) of mRNAs that contain premature stop codons. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 76 kDa

ID gène: 74108

UniProt: Q8VDG3