anticorps RASGRP3, anticorps zgc:162151, anticorps GRP3, anticorps BC066069, anticorps Gm327, anticorps RAS guanyl releasing protein 3, anticorps RAS guanyl releasing protein 3 (calcium and DAG-regulated), anticorps RAS, guanyl releasing protein 3, anticorps RASGRP3, anticorps rasgrp3, anticorps Rasgrp3
Sujet
Members of the RAS (see HRAS, MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.