p130 anticorps
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- Antigène Voir toutes p130 (RBL2) Anticorps
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
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Reactivité
- Rat, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp p130 est non-conjugé
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Application
- Immunofluorescence (IF), Immunohistochemistry (IHC)
- Réactivité croisée
- Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse Rb2 p130
- Top Product
- Discover our top product RBL2 Anticorps primaire
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anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 165-194), (N-Term) antibody
RBL2 Reactivité: Humain WB, FACS Hôte: Lapin Polyclonal RB31021 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 939-1139) antibodyRBL2 Reactivité: Humain ELISA, WB, FACS Hôte: Souris Monoclonal 2C8A8 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 26-367) antibodyRBL2 Reactivité: Humain, Rat, Souris, Blow Fly, Poulet WB, IF, IHC, IP Hôte: Souris Monoclonal 10-Rb2 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 100-200) antibodyRBL2 Reactivité: Humain WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 878-913) antibodyRBL2 Reactivité: Humain, Rat WB, IF, IHC, IHC (p), IP Hôte: Souris Monoclonal 130P215 unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 417-616) antibodyRBL2 Reactivité: Humain ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Humain, Rat, Souris WB Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Humain, Rat, Souris ELISA, IHC Hôte: Lapin Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) (AA 416-515) antibodyRBL2 Reactivité: Humain ELISA, WB Hôte: Souris Polyclonal unconjugated
anti-Retinoblastoma-Like 2 (p130) (RBL2) antibodyRBL2 Reactivité: Humain, Chimpanzé ELISA, WB Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- IHC/IF (M,R) 1:500-1:1500
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- p130 (RBL2) (Retinoblastoma-Like 2 (p130) (RBL2))
- Autre désignation
- Rb2 p130 (RBL2 Produits)
- Synonymes
- anticorps RBL2, anticorps RBR2, anticorps RRB2a, anticorps PRB2, anticorps RBR-2, anticorps Rb2, anticorps p130, anticorps P130, anticorps retinoblastoma-like 2 (p130), anticorps RB transcriptional corepressor like 2, anticorps related to retinoblastoma 2, anticorps RBL2, anticorps LOC541652, anticorps Rbl2
- Sujet
- RBL2 (also known as p130) or Retinoblastoma-like protein 2 is a key regulator of entry into cell division. It is directly involved in heterochromatin formation by maintaining overall chromatin structure and (in particular) that of constitutive heterochromatin by stabilizing histone methylation. RBL2 recruits and targets histone methyltransferases KMT5B and KMT5C leading to epigenetic transcriptional repression. It controls histone H4 'Lys20' trimethylation. It probably also acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. RBL2 serves as a potent inhibitor of E2F-mediated trans-activation and associates preferentially with E2F5.
- ID gène
- 19651
- NCBI Accession
- NP_001268929
- UniProt
- Q64700
- Pathways
- Cycle Cellulaire, Mitotic G1-G1/S Phases
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