ARHGAP17 anticorps

N° du produit ABIN7075416

Détail du produit anti-ARHGAP17 anticorps

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Reactivité: Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGAP17 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse ARHGAP17

Information d'application

Indications d'application: WB (M) 1:250-1:500, IHC/IF (R) 1:500-1:1500

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur ARHGAP17

Antigène: ARHGAP17 (rho GTPase Activating Protein 17 (ARHGAP17))

Autre désignation: ARHGAP17 (ARHGAP17 Produits)

Sujet: ARHGAP17 is a Rho GTPase-activating protein involved in the maintenance of tight junction by regulating the activity of CDC42, thereby playing a central role in apical polarity of epithelial cells. It specifically acts as a GTPase activator for the CDC42 GTPase by converting it to an inactive GDP-bound state. RHGAP17 participates in the Ca(2+)-dependent regulation of exocytosis, possibly by catalyzing GTPase activity of Rho family proteins and by inducing the reorganization of the cortical actin filaments. Acts as a GTPase activator in vitro for RAC1.

Poids moléculaire: 81 kDa

ID gène: 70497

NCBI Accession: NP_001116112

UniProt: Q3UIA2