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RNF7 anticorps

RNF7 Reactivité: Humain, Souris, Rat IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7075471
  • Antigène Voir toutes RNF7 Anticorps
    RNF7 (Ring Finger Protein 7 (RNF7))
    Reactivité
    Humain, Souris, Rat
    Hôte
    • 21
    • 1
    Lapin
    Clonalité
    • 22
    Polyclonal
    Conjugué
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp RNF7 est non-conjugé
    Application
    • 10
    • 10
    • 4
    • 4
    • 1
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    KLH conjugated Synthetic peptide corresponding to Mouse RNF7
  • Indications d'application
    IHC/IF (H,M,R) 1:500-1:2000/1:500-1:3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    RNF7 (Ring Finger Protein 7 (RNF7))
    Autre désignation
    RNF7 (RNF7 Produits)
    Synonymes
    anticorps CKBBP1, anticorps ROC2, anticorps SAG, anticorps Rbx2, anticorps ring finger protein 7, anticorps RNF7, anticorps Rnf7
    Sujet
    The RNF7 is probable a component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
    ID gène
    19823
    NCBI Accession
    NP_001298064
    UniProt
    Q9WTZ1
    Pathways
    Positive Regulation of Endopeptidase Activity
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