SAV1 anticorps

N° du produit ABIN7075505

Détail du produit anti-SAV1 anticorps

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SAV1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunofluorescence (IF)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse SAV1

Information d'application

Indications d'application: IHC/IF (M,R) 1:200-1:1400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur SAV1

Antigène: SAV1 (Salvador Homolog 1 (SAV1))

Autre désignation: SAV1 (SAV1 Produits)

Synonymes: anticorps SAV, anticorps WW45, anticorps WWP4, anticorps 1700040G09Rik, anticorps Salv, anticorps Sav, anticorps Wwp3, anticorps Wwp4, anticorps salvador family WW domain containing protein 1, anticorps salvador family WW domain containing 1, anticorps SAV1, anticorps Sav1

Sujet: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

ID gène: 64010

NCBI Accession: NP_071311

UniProt: Q8VEB2

Pathways: Stem Cell Maintenance