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KDM3B anticorps (AA 1601-1761)

KDM3B Reactivité: Humain, Souris, Rat WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN704651
  • Antigène Voir toutes KDM3B Anticorps
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Épitope
    • 14
    • 8
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1601-1761
    Reactivité
    • 59
    • 35
    • 22
    • 7
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 60
    • 1
    Lapin
    Clonalité
    • 61
    Polyclonal
    Conjugué
    • 31
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp KDM3B est non-conjugé
    Application
    • 47
    • 21
    • 12
    • 12
    • 7
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
     Réactivité croisée
    Humain, Souris, Rat
    Homologie
    Dog,Cow,Pig,Rabbit
    Purification
    Purified by Protein A.
    Immunogène
    KLH conjugated synthetic peptide derived from human JMJD1B
    Isotype
    IgG
    Top Product
    Discover our top product KDM3B Anticorps primaire
  • Indications d'application
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Agent conservateur
    ProClin
    Précaution d'utilisation
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Date de péremption
    12 months
  • Antigène
    KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))
    Autre désignation
    JMJD1B (KDM3B Produits)
    Synonymes
    anticorps KDM3B, anticorps JMJD1B, anticorps 5830462I21Rik, anticorps JHDM2B, anticorps Jmjd1b, anticorps mKIAA1082, anticorps 5qNCA, anticorps C5orf7, anticorps NET22, anticorps lysine demethylase 3B, anticorps lysine (K)-specific demethylase 3B, anticorps lysine-specific demethylase 3B, anticorps KDM3B lysine (K)-specific demethylase 3B, anticorps KDM3B, anticorps LOC100540242, anticorps kdm3b, anticorps Kdm3b
    Sujet

    Synonyms: JHDM2B, JmjC domain containing histone demethylation protein 2B, JmjC domain-containing histone demethylation protein 2B , jmjd1b, Jumonji domain containing protein 1B, JUMONJI DOMAIN-CONTAINING PROTEIN 1B , KDM3B, KDM3B_HUMAN, Lysine-specic demethylase 3B, Nuclear protein 5qNCA.

    Background: JMJD1B (jumonji domain containing 1B), also known as KDM3B, 5qNCA (5q Nuclear Co-Activator) or C5orf7, is a member of the JHDM2 histone demethylase family of proteins. Expressed in a wide variety of tissues, JMJD1B localizes to the nucleus and contains one JMJC domain and a C-terminal zinc finger motif. JMJD1B functions as a histone demethylase and, using iron as a cofactor, demethylates lysine-9 of Histone H3. This suggests that JMJD1B plays a central role in the histone code. The gene encoding human JMJD1B is located within the 5q region of the genome that is often deleted in myeloid leukemias and myelodysplasias. This implies that JMJD1B may function as a tumor suppressor of myeloid leukemia. Eptopic expression of JMJD1B exhibits growth suppressive activities, further supporting a role for JMJD1B in tumor suppression.

    ID gène
    51780
    Pathways
    L'effet Warburg
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