TEX264 anticorps

N° du produit ABIN7075863

Détail du produit anti-TEX264 anticorps

Antigène: TEX264 (Testis Expressed 264 (TEX264))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TEX264 est non-conjugé

Application: Western Blotting (WB)

Réactivité croisée: Rat

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse TEX264

Information d'application

Indications d'application: WB (M,R) 1:1000-1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur TEX264

Antigène: TEX264 (Testis Expressed 264 (TEX264))

Autre désignation: TEX264 (TEX264 Produits)

Synonymes: anticorps ZSIG11, anticorps TEG-264, anticorps testis expressed 264, anticorps testis expressed gene 264, anticorps TEX264, anticorps Tex264

Sujet: Major reticulophagy (also called ER-phagy) receptor that acts independently of other candidate reticulophagy receptors to remodel subdomains of the endoplasmic reticulum into autophagosomes upon nutrient stress, which then fuse with lysosomes for endoplasmic reticulum turnover. The ATG8-containing isolation membrane (IM) cradles a tubular segment of TEX264-positive ER near a three-way junction, allowing the formation of a synapse of 2 juxtaposed membranes with trans interaction between the TEX264 and ATG8 proteins. Expansion of the IM would extend the capture of ER, possibly through a 'zipper-like' process involving continued trans TEX264-ATG8 interactions, until poorly understood mechanisms lead to the fission of relevant membranes and, ultimately, autophagosomal membrane closure.

Poids moléculaire: 34 kDa

UniProt: Q99LS5