Cet anticorps Lapin Polyclonal détecte spécifiquement Topoisomerase II alpha dans IHC et IF. Il présente une réactivité avec des échantillons de Souris et Rat.
TOP2A
Reactivité: Humain
WB, IHC (p)
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
IHC/IF (M,R) 1:600-1:2000/1:500-1:1000
Restrictions
For Research Use only
Format
Liquid
Buffer
PBS, pH 7.4, 0.02 % sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Antigène
Topoisomerase II alpha (TOP2A)
(Topoisomerase (DNA) II alpha 170kDa (TOP2A))
Autre désignation
Topoisomerase II alpha
Sujet
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event.