UAP1L1 anticorps

N° du produit ABIN7076143

Détail du produit anti-UAP1L1 anticorps

Antigène: UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp UAP1L1 est non-conjugé

Application: Western Blotting (WB)

Purification: Affinity purification

Immunogène: Recombinant protein corresponding to Mouse UAP1L1

Information d'application

Indications d'application: WB (M) 1:2000- 1:4000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, pH 7.4, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur UAP1L1

Antigène: UAP1L1 (UDP-N-Acteylglucosamine Pyrophosphorylase 1-Like 1 (UAP1L1))

Autre désignation: UAP1L1 (UAP1L1 Produits)

Synonymes: anticorps RP11-229P13.18, anticorps 5730445F03Rik, anticorps zgc:56509, anticorps UDP-N-acetylglucosamine pyrophosphorylase 1 like 1, anticorps UDP-N-acteylglucosamine pyrophosphorylase 1-like 1, anticorps UDP-N-acetylglucosamine pyrophosphorylase 1, like 1, anticorps UAP1L1, anticorps Uap1l1, anticorps uap1l1

Sujet: UAP1 is a 56KDa isoform which catalyzes the final step of UDP-N-acetylglucosamine (UDP-GlcNAc) biosynthesis from fructose-6-phosphate. UDP-GlcNAc, the activated form of GlcNAc moiety is used as a key precursor in N-linked glycosylation and the glycosylphosphatidylinositol (GPI)-anchor of cellular proteins. Crystallization studies revealed UAP1 is composed of a large central core flanked by two smaller extra domains. The central main domain displays a alpha/beta structure resembling the Rossmann fold. Northern Blot analysis detected abundant expression of UAP1 in testis and sperm with a low expression in placenta, muscle and liver. It is implicated in antibody-mediated infertility in males.

Poids moléculaire: 57 kDa

ID gène: 227620

NCBI Accession: NP_001028465

UniProt: Q3TW96