ZNF746 anticorps
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- Antigène Voir toutes ZNF746 Anticorps
- ZNF746 (Zinc Finger Protein 746 (ZNF746))
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp ZNF746 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Réactivité croisée
- Humain, Rat
- Purification
- Affinity purification
- Immunogène
- Recombinant protein corresponding to Mouse PARIS
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- Indications d'application
- WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS, pH 7.4, 0.02 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
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- Antigène
- ZNF746 (Zinc Finger Protein 746 (ZNF746))
- Autre désignation
- PARIS (ZNF746 Produits)
- Synonymes
- anticorps PARIS, anticorps 2810407L07Rik, anticorps AI317225, anticorps Znf746, anticorps RGD1306209, anticorps zinc finger protein 746, anticorps ZNF746, anticorps Zfp746
- Sujet
- ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.
- Poids moléculaire
- 100 kDa
- ID gène
- 69228
- NCBI Accession
- NP_001156947
- UniProt
- Q3U133
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