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ZNF746 anticorps

ZNF746 Reactivité: Humain, Souris, Rat WB, IHC, IF Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN7076272
  • Antigène Voir toutes ZNF746 Anticorps
    ZNF746 (Zinc Finger Protein 746 (ZNF746))
    Reactivité
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 5
    • 1
    Lapin
    Clonalité
    • 5
    • 1
    Polyclonal
    Conjugué
    • 6
    Cet anticorp ZNF746 est non-conjugé
    Application
    • 6
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
     Réactivité croisée
    Humain, Rat
    Purification
    Affinity purification
    Immunogène
    Recombinant protein corresponding to Mouse PARIS
  • Indications d'application
    WB (H) 1:500-1:1000, IHC/IF (M,R) 1:1500-1:3000/1:1500-1:3000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS, pH 7.4, 0.02 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
  • Antigène
    ZNF746 (Zinc Finger Protein 746 (ZNF746))
    Autre désignation
    PARIS (ZNF746 Produits)
    Synonymes
    anticorps PARIS, anticorps 2810407L07Rik, anticorps AI317225, anticorps Znf746, anticorps RGD1306209, anticorps zinc finger protein 746, anticorps ZNF746, anticorps Zfp746
    Sujet
    ZNF746, also named as PARIS, which belongs to the krueppel C2H2-type zinc-finger protein family. ZNF746 mainly localizes to the cytoplasm and probably translocates to the nucleus to repress selected genes. ZNF746 as a transcription repressor that specifically binds to the 5'-TATTTT[T/G]-3' consensus sequence on promoters and repress transcription of PGC-1-alpha (PPARGC1A), thereby playing a role in regulation of neuron death. ZNF746 may act as a downstream effector of PRKN and contribute to neurodegeneration in Parkinson disease cases caused by defects in PRKN.
    Poids moléculaire
    100 kDa
    ID gène
    69228
    NCBI Accession
    NP_001156947
    UniProt
    Q3U133
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