CD276 anticorps (Biotin)
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- Antigène Voir toutes CD276 Anticorps
- CD276
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD276 est conjugé à/à la Biotin
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Application
- Flow Cytometry (FACS)
- Fonction
- CD276 Biotin Antibody
- Attributs du produit
- The clone DCN.70, a mouse monoclonal antibody selectively binds with a k type I membrane protein commonly known as CD276, a member of B7-H3 immunoregulatory family. It is not expressed by lymphocytes or granulocytes but weakly expressed on resting monocytes. Increased expression is observed on monocytes derived dendritic cells as well as in a variety of cancer types, including breast, pancreatic, and ovarian cancer. CD276 expression has been correlated with poor survival in ovarian cancer subjects. CD276 blockade, especially when combined with an anti-PD-1 blockade, is a promising strategy for the treatment of B7-H3-expressing NSCLCs that arerefractory to anti-PD-1 therapy, making CD276 a promising clinical molecular target.
- Purification
- Purified
- Pureté
- >95 %
- Classe de qualité
- GMP Grade
- Immunogène
- Human Dendritic Cells
- Clone
- DCN-70
- Isotype
- IgG1, kappa
- Top Product
- Discover our top product CD276 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS pH 7.2, 0.09 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- 2-8°C, Conjugated antibodies should never be frozen.
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- Antigène
- CD276
- Autre désignation
- CD276 (CD276 Produits)
- Synonymes
- anticorps sc:d0645, anticorps zgc:158279, anticorps 6030411F23Rik, anticorps AU016588, anticorps B7RP-2, anticorps B7h3, anticorps B7H3, anticorps 4Ig-B7-H3, anticorps B7-H3, anticorps CD276 molecule, anticorps CD276 molecule S homeolog, anticorps CD276 antigen, anticorps Cd276 molecule, anticorps CD276, anticorps cd276.S, anticorps cd276, anticorps Cd276
- ID gène
- 80381
- UniProt
- Q5ZPR3
- Pathways
- Cancer Immune Checkpoints
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