TSC1 anticorps (AA 131-230)
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- Antigène Voir toutes TSC1 Anticorps
- TSC1 (Tuberous Sclerosis 1 (TSC1))
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Épitope
- AA 131-230
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Reactivité
- Mouton
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp TSC1 est non-conjugé
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Application
- ELISA, Western Blotting (WB)
- Réactivité croisée
- Mouton
- Homologie
- Human,Mouse,Rat,Dog,Cow,Pig,Horse
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Hamartin
- Isotype
- IgG
- Top Product
- Discover our top product TSC1 Anticorps primaire
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- Indications d'application
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WB 1:300-5000
ELISA 1:500-1000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Date de péremption
- 12 months
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DNA methylation Landscape of body size variation in sheep." dans: Scientific reports, Vol. 5, pp. 13950, (2016) (PubMed).
: "
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DNA methylation Landscape of body size variation in sheep." dans: Scientific reports, Vol. 5, pp. 13950, (2016) (PubMed).
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- Antigène
- TSC1 (Tuberous Sclerosis 1 (TSC1))
- Autre désignation
- Hamartin/TSC1 (TSC1 Produits)
- Synonymes
- anticorps LAM, anticorps TSC, anticorps hamartin, anticorps mKIAA0243, anticorps tsc1, anticorps wu:fc38b04, anticorps fa99f04, anticorps wu:fa99f04, anticorps zgc:63657, anticorps TSC complex subunit 1, anticorps tuberous sclerosis 1, anticorps TSC complex subunit 1b, anticorps TSC complex subunit 1a, anticorps TSC1, anticorps Tsc1, anticorps tsc1b, anticorps tsc1, anticorps tsc1a
- Sujet
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Synonyms: LAM, TSC1, Tuberous sclerosis 1 protein, TSC1_HUMAN.
Background: Hamartin, or TSC1, is a suspected tumor suppressor implicated in the disease tuberous sclerosis 1. It is a negative regulator of cell division controlling the transition from G0/G1 to S phase, and it seems to act through the phosphatidylinositol 3 kinase/Akt pathway. TSC1 interacts with tuberin m(TSC2), which is thought to be a GAP (GTPase Activating Protein) for the Rap1 and Rab5 small G Proteins. The Hamartin/Tuberin complex has been shown to inhibit mTor. Hamartin has also been shown to interact with ERM (Ezrin-Radixin-Moesin) proteins and with F-actin, suggesting a role for TSC proteins in modulation of cell adhesion and morphology.
- ID gène
- 7248
- UniProt
- Q92574
- Pathways
- Signalisation RTK, AMPK Signaling, Regulation of Cell Size, Tube Formation
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